HCSGD entry for KCNE2

1. General information

Official gene symbolKCNE2
Entrez ID9992
Gene full namepotassium voltage-gated channel, Isk-related family, member 2
Other gene symbolsATFB4 LQT5 LQT6 MIRP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005242Inward rectifier potassium channel activityIDAmolecular_function
GO:0005251Delayed rectifier potassium channel activityIDAmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007568AgingIEAbiological_process
GO:0008076Voltage-gated potassium channel complexIDAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0010107Potassium ion importIMPbiological_process
GO:0015459Potassium channel regulator activityIDAmolecular_function
GO:0034613Cellular protein localizationIEAbiological_process
GO:0035690Cellular response to drugIDAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043586Tongue developmentIEAbiological_process
GO:0044325Ion channel bindingIDAmolecular_function
GO:0060306Regulation of membrane repolarizationIDAbiological_process
GO:0060307Regulation of ventricular cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0071435Potassium ion exportIDAbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
GO:0086002Cardiac muscle cell action potential involved in contractionIMPbiological_process
GO:0086005Ventricular cardiac muscle cell action potentialIMPbiological_process
GO:0086009Membrane repolarizationIDAbiological_process
GO:0086011Membrane repolarization during action potentialIMPbiological_process
GO:0086013Membrane repolarization during cardiac muscle cell action potentialIMPbiological_process
GO:0086091Regulation of heart rate by cardiac conductionIMPbiological_process
GO:1901379Regulation of potassium ion transmembrane transportIDAbiological_process
GO:1901800Positive regulation of proteasomal protein catabolic processIDAbiological_process
GO:1901979Regulation of inward rectifier potassium channel activityIDAbiological_process
GO:1902159Regulation of cyclic nucleotide-gated ion channel activityIEAbiological_process
GO:1902259Regulation of delayed rectifier potassium channel activityIDAbiological_process
GO:1902282Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationIMPmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82062232440.55464326960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0132759289
GSE13712_SHEARDown-0.1743296599
GSE13712_STATICUp0.0440824965
GSE19018Up0.0572863918
GSE19899_A1Up0.1251602572
GSE19899_A2Up0.1268653864
PubMed_21979375_A1Down-0.1083018089
PubMed_21979375_A2Down-0.6776511807
GSE35957Up0.1393979885
GSE36640Up0.1453934170
GSE54402Down-0.0890608151
GSE9593Up0.1403433325
GSE43922Down-0.0027426632
GSE24585Down-0.0431894847
GSE37065Up0.1209035542
GSE28863_A1Down-0.1421408921
GSE28863_A2Down-0.1655845393
GSE28863_A3Up0.1523658144
GSE28863_A4Up0.0080765186
GSE48662Down-0.0375091772

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.