HCSGD entry for PTBP3


1. General information

Official gene symbolPTBP3
Entrez ID9991
Gene full namepolypyrimidine tract binding protein 3
Other gene symbolsROD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006397MRNA processingIEAbiological_process
GO:0008380RNA splicingIEAbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0033119Negative regulation of RNA splicingIDAbiological_process
GO:0043249Erythrocyte maturationIEAbiological_process
GO:0045595Regulation of cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21639092740.47479142510.89567947951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1576042378
GSE13712_SHEARUp0.0663833530
GSE13712_STATICDown-0.0085453536
GSE19018Up0.2597378119
GSE19899_A1Up0.2221684241
GSE19899_A2Up0.1229555643
PubMed_21979375_A1Up0.6408909913
PubMed_21979375_A2Up0.4518067234
GSE35957Up0.3769233781
GSE36640Down-0.7937835388
GSE54402Up0.2130443971
GSE9593Down-0.2581105193
GSE43922Up0.2570225911
GSE24585Up0.0477254760
GSE37065Up0.0235105210
GSE28863_A1Down-0.1406925986
GSE28863_A2Up0.0092821115
GSE28863_A3Down-0.4357888983
GSE28863_A4Up0.0316159036
GSE48662Down-0.2446331752

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022729Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-221-3pMIMAT0000278MIRT024160SequencingFunctional MTI (Weak)20371350
hsa-miR-21-5pMIMAT0000076MIRT030890MicroarrayFunctional MTI (Weak)18591254
hsa-miR-1229-3pMIMAT0005584MIRT036365CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041782CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042966CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT047996CLASHFunctional MTI (Weak)23622248
hsa-miR-197-3pMIMAT0000227MIRT048115CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.