HCSGD entry for PTBP3
1. General information
| Official gene symbol | PTBP3 |
|---|---|
| Entrez ID | 9991 |
| Gene full name | polypyrimidine tract binding protein 3 |
| Other gene symbols | ROD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0033119 | Negative regulation of RNA splicing | IDA | biological_process |
| GO:0043249 | Erythrocyte maturation | IEA | biological_process |
| GO:0045595 | Regulation of cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2163909274 | 0.4747914251 | 0.8956794795 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1576042378 |
| GSE13712_SHEAR | Up | 0.0663833530 |
| GSE13712_STATIC | Down | -0.0085453536 |
| GSE19018 | Up | 0.2597378119 |
| GSE19899_A1 | Up | 0.2221684241 |
| GSE19899_A2 | Up | 0.1229555643 |
| PubMed_21979375_A1 | Up | 0.6408909913 |
| PubMed_21979375_A2 | Up | 0.4518067234 |
| GSE35957 | Up | 0.3769233781 |
| GSE36640 | Down | -0.7937835388 |
| GSE54402 | Up | 0.2130443971 |
| GSE9593 | Down | -0.2581105193 |
| GSE43922 | Up | 0.2570225911 |
| GSE24585 | Up | 0.0477254760 |
| GSE37065 | Up | 0.0235105210 |
| GSE28863_A1 | Down | -0.1406925986 |
| GSE28863_A2 | Up | 0.0092821115 |
| GSE28863_A3 | Down | -0.4357888983 |
| GSE28863_A4 | Up | 0.0316159036 |
| GSE48662 | Down | -0.2446331752 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022729 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024160 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030890 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036365 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041782 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042966 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047996 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048115 | CLASH | Functional MTI (Weak) | 23622248 |
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