HCSGD entry for SLC23A1

1. General information

Official gene symbolSLC23A1
Entrez ID9963
Gene full namesolute carrier family 23 (nucleobase transporters), member 1
Other gene symbolsSLC23A2 SVCT1 YSPL3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005903Brush borderIEAcellular_component
GO:0006139Nucleobase-containing compound metabolic processTASbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006814Sodium ion transportIDAbiological_process
GO:0007420Brain developmentISSbiological_process
GO:0008520L-ascorbate:sodium symporter activityIDAmolecular_function
GO:0009636Response to toxic substanceIDAbiological_process
GO:0009925Basal plasma membraneIEAcellular_component
GO:0015081Sodium ion transmembrane transporter activityIDAmolecular_function
GO:0015205Nucleobase transmembrane transporter activityTASmolecular_function
GO:0015229L-ascorbic acid transporter activityIDAmolecular_function
GO:0015851Nucleobase transportTASbiological_process
GO:0015882L-ascorbic acid transportIDAbiological_process
GO:0015931Nucleobase-containing compound transportTASbiological_process
GO:0016020MembraneIEA TAScellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019852L-ascorbic acid metabolic processTASbiological_process
GO:0030324Lung developmentIEAbiological_process
GO:0033300Dehydroascorbic acid transporter activityIMPmolecular_function
GO:0034219Carbohydrate transmembrane transportIDAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0035461Vitamin transmembrane transportIDAbiological_process
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0043229Intracellular organelleIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportIEAbiological_process
GO:0070837Dehydroascorbic acid transportIMPbiological_process
GO:0070890Sodium-dependent L-ascorbate transmembrane transporter activityIDAmolecular_function
GO:0070904Transepithelial L-ascorbic acid transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85387881160.63114461080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0464346845
GSE13712_SHEARDown-0.0186451506
GSE13712_STATICDown-0.2031902796
GSE19018Up0.0402484072
GSE19899_A1Down-0.0405068890
GSE19899_A2Down-0.1690299668
PubMed_21979375_A1Down-0.2860364081
PubMed_21979375_A2Up0.1330657546
GSE35957Up0.0267151961
GSE36640Up0.0430571610
GSE54402Down-0.0295091676
GSE9593Down-0.0457358478
GSE43922Up0.0139339402
GSE24585Up0.0739527201
GSE37065Up0.0597406067
GSE28863_A1Down-0.0675259433
GSE28863_A2Up0.0361578150
GSE28863_A3Up0.1463589199
GSE28863_A4Down-0.0357759333
GSE48662Down-0.0076757139

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.