HCSGD entry for SLC23A1

1. General information

Official gene symbolSLC23A1
Entrez ID9963
Gene full namesolute carrier family 23 (nucleobase transporters), member 1
Other gene symbolsSLC23A2 SVCT1 YSPL3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005903Brush borderIEAcellular_component
GO:0006139Nucleobase-containing compound metabolic processTASbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006814Sodium ion transportIDAbiological_process
GO:0007420Brain developmentISSbiological_process
GO:0008520L-ascorbate:sodium symporter activityIDAmolecular_function
GO:0009636Response to toxic substanceIDAbiological_process
GO:0009925Basal plasma membraneIEAcellular_component
GO:0015081Sodium ion transmembrane transporter activityIDAmolecular_function
GO:0015205Nucleobase transmembrane transporter activityTASmolecular_function
GO:0015229L-ascorbic acid transporter activityIDAmolecular_function
GO:0015851Nucleobase transportTASbiological_process
GO:0015882L-ascorbic acid transportIDAbiological_process
GO:0015931Nucleobase-containing compound transportTASbiological_process
GO:0016020MembraneIEA TAScellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019852L-ascorbic acid metabolic processTASbiological_process
GO:0030324Lung developmentIEAbiological_process
GO:0033300Dehydroascorbic acid transporter activityIMPmolecular_function
GO:0034219Carbohydrate transmembrane transportIDAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0035461Vitamin transmembrane transportIDAbiological_process
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0043229Intracellular organelleIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportIEAbiological_process
GO:0070837Dehydroascorbic acid transportIMPbiological_process
GO:0070890Sodium-dependent L-ascorbate transmembrane transporter activityIDAmolecular_function
GO:0070904Transepithelial L-ascorbic acid transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85387881160.63114461080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0464346845
GSE13712_SHEARDown-0.0186451506
GSE13712_STATICDown-0.2031902796
GSE19018Up0.0402484072
GSE19899_A1Down-0.0405068890
GSE19899_A2Down-0.1690299668
PubMed_21979375_A1Down-0.2860364081
PubMed_21979375_A2Up0.1330657546
GSE35957Up0.0267151961
GSE36640Up0.0430571610
GSE54402Down-0.0295091676
GSE9593Down-0.0457358478
GSE43922Up0.0139339402
GSE24585Up0.0739527201
GSE37065Up0.0597406067
GSE28863_A1Down-0.0675259433
GSE28863_A2Up0.0361578150
GSE28863_A3Up0.1463589199
GSE28863_A4Down-0.0357759333
GSE48662Down-0.0076757139

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Vitamin CDB00126 NUTR00001 | APRD00084 | EXPT00568 | DB09541

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.