HCSGD entry for SLC23A2

1. General information

Official gene symbolSLC23A2
Entrez ID9962
Gene full namesolute carrier family 23 (nucleobase transporters), member 2
Other gene symbolsNBTL1 SLC23A1 SVCT2 YSPL2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006139Nucleobase-containing compound metabolic processTASbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006979Response to oxidative stressIEAbiological_process
GO:0008520L-ascorbate:sodium symporter activityIEAmolecular_function
GO:0008523Sodium-dependent multivitamin transmembrane transporter activityNASmolecular_function
GO:0009925Basal plasma membraneIEAcellular_component
GO:0015205Nucleobase transmembrane transporter activityTASmolecular_function
GO:0015229L-ascorbic acid transporter activityIDAmolecular_function
GO:0015851Nucleobase transportTASbiological_process
GO:0015882L-ascorbic acid transportIDAbiological_process
GO:0015931Nucleobase-containing compound transportTASbiological_process
GO:0015993Molecular hydrogen transportNASbiological_process
GO:0016020MembraneIEA TAScellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0019852L-ascorbic acid metabolic processNAS TASbiological_process
GO:0034219Carbohydrate transmembrane transportIDAbiological_process
GO:0034220Ion transmembrane transportIDA NASbiological_process
GO:0035461Vitamin transmembrane transportIDA NASbiological_process
GO:0035725Sodium ion transmembrane transportIDA NASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportIEAbiological_process
GO:0070890Sodium-dependent L-ascorbate transmembrane transporter activityIDAmolecular_function
GO:0070904Transepithelial L-ascorbic acid transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58370254170.21549759890.99999024730.8951825154

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0375434102
GSE13712_SHEARDown-0.1580832599
GSE13712_STATICDown-0.1763559487
GSE19018Down-0.0857234758
GSE19899_A1Down-0.1107066804
GSE19899_A2Down-0.1081053467
PubMed_21979375_A1Down-0.6555854030
PubMed_21979375_A2Down-0.1355410447
GSE35957Up0.2138642493
GSE36640Up0.3646560414
GSE54402Down-0.2951662397
GSE9593Up0.2308442283
GSE43922Down-0.4635971919
GSE24585Down-0.1583391113
GSE37065Up0.0264569589
GSE28863_A1Up0.8400602862
GSE28863_A2Up0.4340026822
GSE28863_A3Down-0.3578753587
GSE28863_A4Down-0.1382549866
GSE48662Up0.1693922475

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320bMIMAT0005792MIRT036183CLASHFunctional MTI (Weak)23622248
hsa-miR-196b-5pMIMAT0001080MIRT042667CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.