HCSGD entry for SEPT7
1. General information
| Official gene symbol | SEPT7 |
|---|---|
| Entrez ID | 989 |
| Gene full name | septin 7 |
| Other gene symbols | CDC10 CDC3 NBLA02942 SEPT7A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000910 | Cytokinesis | TAS | biological_process |
| GO:0001725 | Stress fiber | IDA | cellular_component |
| GO:0005198 | Structural molecule activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005930 | Axoneme | ISS | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0016324 | Apical plasma membrane | ISS | cellular_component |
| GO:0016476 | Regulation of embryonic cell shape | ISS | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0031105 | Septin complex | IEA | cellular_component |
| GO:0032154 | Cleavage furrow | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043679 | Axon terminus | IEA | cellular_component |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0051291 | Protein heterooligomerization | IDA | biological_process |
| GO:0060271 | Cilium morphogenesis | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9354549447 | 0.1094987311 | 0.9999902473 | 0.6333932762 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1751674834 |
| GSE13712_SHEAR | Down | -0.2721730287 |
| GSE13712_STATIC | Up | 0.1135436218 |
| GSE19018 | Down | -0.1173976751 |
| GSE19899_A1 | Down | -0.0364547981 |
| GSE19899_A2 | Down | -0.5810360221 |
| PubMed_21979375_A1 | Down | -0.2127374269 |
| PubMed_21979375_A2 | Down | -0.7948600206 |
| GSE35957 | Up | 0.1676525901 |
| GSE36640 | Down | -0.2097538241 |
| GSE54402 | Down | -0.3877755012 |
| GSE9593 | Down | -0.2277283971 |
| GSE43922 | Down | -0.0456460664 |
| GSE24585 | Up | 0.0346637541 |
| GSE37065 | Down | -0.0696575494 |
| GSE28863_A1 | Up | 0.2763893426 |
| GSE28863_A2 | Down | -0.1422017414 |
| GSE28863_A3 | Up | 0.0570446852 |
| GSE28863_A4 | Up | 0.2102254568 |
| GSE48662 | Up | 0.0642588417 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT007238 | Luciferase reporter assay | Functional MTI | 23383034 |
| hsa-miR-429 | MIMAT0001536 | MIRT016645 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020355 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021078 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021657 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024133 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029829 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047390 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
