HCSGD entry for SEPT7


1. General information

Official gene symbolSEPT7
Entrez ID989
Gene full nameseptin 7
Other gene symbolsCDC10 CDC3 NBLA02942 SEPT7A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0000910CytokinesisTASbiological_process
GO:0001725Stress fiberIDAcellular_component
GO:0005198Structural molecule activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005930AxonemeISScellular_component
GO:0007049Cell cycleIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0016476Regulation of embryonic cell shapeISSbiological_process
GO:0030496MidbodyIEAcellular_component
GO:0031105Septin complexIEAcellular_component
GO:0032154Cleavage furrowIEAcellular_component
GO:0042802Identical protein bindingIPImolecular_function
GO:0043679Axon terminusIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0051291Protein heterooligomerizationIDAbiological_process
GO:0060271Cilium morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93545494470.10949873110.99999024730.6333932762

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1751674834
GSE13712_SHEARDown-0.2721730287
GSE13712_STATICUp0.1135436218
GSE19018Down-0.1173976751
GSE19899_A1Down-0.0364547981
GSE19899_A2Down-0.5810360221
PubMed_21979375_A1Down-0.2127374269
PubMed_21979375_A2Down-0.7948600206
GSE35957Up0.1676525901
GSE36640Down-0.2097538241
GSE54402Down-0.3877755012
GSE9593Down-0.2277283971
GSE43922Down-0.0456460664
GSE24585Up0.0346637541
GSE37065Down-0.0696575494
GSE28863_A1Up0.2763893426
GSE28863_A2Down-0.1422017414
GSE28863_A3Up0.0570446852
GSE28863_A4Up0.2102254568
GSE48662Up0.0642588417

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT007238Luciferase reporter assayFunctional MTI23383034
hsa-miR-429MIMAT0001536MIRT016645Reporter assayFunctional MTI20005803
hsa-miR-200a-3pMIMAT0000682MIRT020355Reporter assayFunctional MTI20005803
hsa-miR-200c-3pMIMAT0000617MIRT021078Reporter assayFunctional MTI20005803
hsa-miR-141-3pMIMAT0000432MIRT021657Reporter assayFunctional MTI20005803
hsa-miR-200b-3pMIMAT0000318MIRT024133Reporter assayFunctional MTI20005803
hsa-miR-26b-5pMIMAT0000083MIRT029829MicroarrayFunctional MTI (Weak)19088304
hsa-miR-34a-5pMIMAT0000255MIRT047390CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.