HCSGD entry for ARHGEF17
1. General information
| Official gene symbol | ARHGEF17 |
|---|---|
| Entrez ID | 9828 |
| Gene full name | Rho guanine nucleotide exchange factor (GEF) 17 |
| Other gene symbols | P164RHOGEF TEM4 p164-RhoGEF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IDA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | TAS | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0097190 | Apoptotic signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9003643631 | 0.0192517382 | 0.9999902473 | 0.2708311064 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4436009148 |
| GSE13712_SHEAR | Down | -0.4360303617 |
| GSE13712_STATIC | Down | -0.5721258327 |
| GSE19018 | Down | -0.1903236644 |
| GSE19899_A1 | Down | -0.6331560120 |
| GSE19899_A2 | Down | -0.7594219127 |
| PubMed_21979375_A1 | Down | -0.9966777533 |
| PubMed_21979375_A2 | Down | -0.0573701745 |
| GSE35957 | Up | 0.6173436885 |
| GSE36640 | Up | 0.1518850782 |
| GSE54402 | Down | -0.3811371957 |
| GSE9593 | Down | -0.3977745564 |
| GSE43922 | Down | -0.4686659706 |
| GSE24585 | Up | 0.1033304167 |
| GSE37065 | Down | -0.3498254460 |
| GSE28863_A1 | Up | 0.5683637105 |
| GSE28863_A2 | Up | 0.2986095362 |
| GSE28863_A3 | Down | -0.2440938770 |
| GSE28863_A4 | Down | -0.1005403282 |
| GSE48662 | Up | 0.1397093843 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
