HCSGD entry for ARHGEF17

1. General information

Official gene symbolARHGEF17
Entrez ID9828
Gene full nameRho guanine nucleotide exchange factor (GEF) 17
Other gene symbolsP164RHOGEF TEM4 p164-RhoGEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0030036Actin cytoskeleton organizationIDAbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90036436310.01925173820.99999024730.2708311064

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4436009148
GSE13712_SHEARDown-0.4360303617
GSE13712_STATICDown-0.5721258327
GSE19018Down-0.1903236644
GSE19899_A1Down-0.6331560120
GSE19899_A2Down-0.7594219127
PubMed_21979375_A1Down-0.9966777533
PubMed_21979375_A2Down-0.0573701745
GSE35957Up0.6173436885
GSE36640Up0.1518850782
GSE54402Down-0.3811371957
GSE9593Down-0.3977745564
GSE43922Down-0.4686659706
GSE24585Up0.1033304167
GSE37065Down-0.3498254460
GSE28863_A1Up0.5683637105
GSE28863_A2Up0.2986095362
GSE28863_A3Down-0.2440938770
GSE28863_A4Down-0.1005403282
GSE48662Up0.1397093843

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.