HCSGD entry for PTDSS1


1. General information

Official gene symbolPTDSS1
Entrez ID9791
Gene full namephosphatidylserine synthase 1
Other gene symbolsPSS1 PSSA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005789Endoplasmic reticulum membraneIEA ISS TAScellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006659Phosphatidylserine biosynthetic processIEA TASbiological_process
GO:0016020MembraneISScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016740Transferase activityIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04980099920.66544573530.48929156401.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5366465431
GSE13712_SHEARDown-0.6717377838
GSE13712_STATICDown-0.1692795007
GSE19018Down-0.3947593859
GSE19899_A1Up0.6242239929
GSE19899_A2Up0.5215231556
PubMed_21979375_A1Up1.2112489602
PubMed_21979375_A2Up0.8868347993
GSE35957Down-0.2303748426
GSE36640Up0.4177862032
GSE54402Up0.1895964947
GSE9593Up0.0534762366
GSE43922Up0.3982245631
GSE24585Down-0.1060296383
GSE37065Down-0.1044376580
GSE28863_A1Up0.1610476319
GSE28863_A2Up0.2210414823
GSE28863_A3Down-0.2525092659
GSE28863_A4Down-0.1760621611
GSE48662Down-0.2035019997

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Phosphatidyl serineDB00144 NUTR00048

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-5pMIMAT0004949MIRT037324CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.