HCSGD entry for PTDSS1
1. General information
| Official gene symbol | PTDSS1 |
|---|---|
| Entrez ID | 9791 |
| Gene full name | phosphatidylserine synthase 1 |
| Other gene symbols | PSS1 PSSA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | IEA ISS TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006659 | Phosphatidylserine biosynthetic process | IEA TAS | biological_process |
| GO:0016020 | Membrane | ISS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0498009992 | 0.6654457353 | 0.4892915640 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5366465431 |
| GSE13712_SHEAR | Down | -0.6717377838 |
| GSE13712_STATIC | Down | -0.1692795007 |
| GSE19018 | Down | -0.3947593859 |
| GSE19899_A1 | Up | 0.6242239929 |
| GSE19899_A2 | Up | 0.5215231556 |
| PubMed_21979375_A1 | Up | 1.2112489602 |
| PubMed_21979375_A2 | Up | 0.8868347993 |
| GSE35957 | Down | -0.2303748426 |
| GSE36640 | Up | 0.4177862032 |
| GSE54402 | Up | 0.1895964947 |
| GSE9593 | Up | 0.0534762366 |
| GSE43922 | Up | 0.3982245631 |
| GSE24585 | Down | -0.1060296383 |
| GSE37065 | Down | -0.1044376580 |
| GSE28863_A1 | Up | 0.1610476319 |
| GSE28863_A2 | Up | 0.2210414823 |
| GSE28863_A3 | Down | -0.2525092659 |
| GSE28863_A4 | Down | -0.1760621611 |
| GSE48662 | Down | -0.2035019997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphatidyl serine | DB00144 | NUTR00048 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037324 | CLASH | Functional MTI (Weak) | 23622248 |
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