HCSGD entry for USP34
1. General information
| Official gene symbol | USP34 |
|---|---|
| Entrez ID | 9736 |
| Gene full name | ubiquitin specific peptidase 34 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004197 | Cysteine-type endopeptidase activity | IMP | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IDA | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6469331636 | 0.1007049618 | 0.9999902473 | 0.6083016044 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3956669813 |
| GSE13712_SHEAR | Up | 0.3567556147 |
| GSE13712_STATIC | Down | -0.0666051855 |
| GSE19018 | Down | -0.0388049151 |
| GSE19899_A1 | Up | 0.1060946438 |
| GSE19899_A2 | Down | -0.1562575229 |
| PubMed_21979375_A1 | Down | -0.3508929512 |
| PubMed_21979375_A2 | Down | -0.1461172629 |
| GSE35957 | Up | 0.1778589217 |
| GSE36640 | Down | -0.1163553560 |
| GSE54402 | Down | -0.0141766240 |
| GSE9593 | Down | -0.0942651301 |
| GSE43922 | Down | -0.0731440429 |
| GSE24585 | Down | -0.3640519297 |
| GSE37065 | Up | 0.0068587849 |
| GSE28863_A1 | Up | 0.6101073828 |
| GSE28863_A2 | Up | 0.8683347083 |
| GSE28863_A3 | Down | -0.6197971288 |
| GSE28863_A4 | Down | -0.3694812865 |
| GSE48662 | Down | -0.1339910532 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026125 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030676 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050448 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
