HCSGD entry for USP34


1. General information

Official gene symbolUSP34
Entrez ID9736
Gene full nameubiquitin specific peptidase 34
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004197Cysteine-type endopeptidase activityIMPmolecular_function
GO:0004221Ubiquitin thiolesterase activityIDAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0071108Protein K48-linked deubiquitinationIDAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64693316360.10070496180.99999024730.6083016044

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3956669813
GSE13712_SHEARUp0.3567556147
GSE13712_STATICDown-0.0666051855
GSE19018Down-0.0388049151
GSE19899_A1Up0.1060946438
GSE19899_A2Down-0.1562575229
PubMed_21979375_A1Down-0.3508929512
PubMed_21979375_A2Down-0.1461172629
GSE35957Up0.1778589217
GSE36640Down-0.1163553560
GSE54402Down-0.0141766240
GSE9593Down-0.0942651301
GSE43922Down-0.0731440429
GSE24585Down-0.3640519297
GSE37065Up0.0068587849
GSE28863_A1Up0.6101073828
GSE28863_A2Up0.8683347083
GSE28863_A3Down-0.6197971288
GSE28863_A4Down-0.3694812865
GSE48662Down-0.1339910532

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-192-5pMIMAT0000222MIRT026125MicroarrayFunctional MTI (Weak)19074876
hsa-miR-21-5pMIMAT0000076MIRT030676MicroarrayFunctional MTI (Weak)18591254
hsa-miR-23a-3pMIMAT0000078MIRT050448CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.