HCSGD entry for SEMA3E
1. General information
| Official gene symbol | SEMA3E |
|---|---|
| Entrez ID | 9723 |
| Gene full name | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| Other gene symbols | M-SEMAH M-SemaK SEMAH coll-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001569 | Patterning of blood vessels | IEA ISS | biological_process |
| GO:0001953 | Negative regulation of cell-matrix adhesion | IEA ISS | biological_process |
| GO:0002040 | Sprouting angiogenesis | IEA ISS | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008360 | Regulation of cell shape | IEA ISS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016525 | Negative regulation of angiogenesis | IEA ISS | biological_process |
| GO:0050808 | Synapse organization | IEA ISS | biological_process |
| GO:0071526 | Semaphorin-plexin signaling pathway | IEA ISS | biological_process |
| GO:2000249 | Regulation of actin cytoskeleton reorganization | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3015672201 | 0.4564803541 | 0.9996978348 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0353237906 |
| GSE13712_SHEAR | Down | -0.0494323725 |
| GSE13712_STATIC | Down | -0.1238970146 |
| GSE19018 | Down | -0.5511802292 |
| GSE19899_A1 | Up | 0.2484954740 |
| GSE19899_A2 | Up | 0.1233015614 |
| PubMed_21979375_A1 | Down | -0.2468631099 |
| PubMed_21979375_A2 | Down | -0.0478189320 |
| GSE35957 | Up | 0.5104287248 |
| GSE36640 | Up | 0.6496395713 |
| GSE54402 | Down | -0.2738324821 |
| GSE9593 | Up | 0.1812480033 |
| GSE43922 | Down | -0.2480986275 |
| GSE24585 | Down | -0.2031167371 |
| GSE37065 | Up | 0.7455998411 |
| GSE28863_A1 | Down | -0.0779405578 |
| GSE28863_A2 | Up | 0.0961525261 |
| GSE28863_A3 | Up | 0.1802955581 |
| GSE28863_A4 | Up | 0.0059180314 |
| GSE48662 | Up | 0.0338808679 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040087 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
