HCSGD entry for SEMA3E


1. General information

Official gene symbolSEMA3E
Entrez ID9723
Gene full namesema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Other gene symbolsM-SEMAH M-SemaK SEMAH coll-5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001569Patterning of blood vesselsIEA ISSbiological_process
GO:0001953Negative regulation of cell-matrix adhesionIEA ISSbiological_process
GO:0002040Sprouting angiogenesisIEA ISSbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0007411Axon guidanceTASbiological_process
GO:0008360Regulation of cell shapeIEA ISSbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016525Negative regulation of angiogenesisIEA ISSbiological_process
GO:0050808Synapse organizationIEA ISSbiological_process
GO:0071526Semaphorin-plexin signaling pathwayIEA ISSbiological_process
GO:2000249Regulation of actin cytoskeleton reorganizationIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30156722010.45648035410.99969783481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0353237906
GSE13712_SHEARDown-0.0494323725
GSE13712_STATICDown-0.1238970146
GSE19018Down-0.5511802292
GSE19899_A1Up0.2484954740
GSE19899_A2Up0.1233015614
PubMed_21979375_A1Down-0.2468631099
PubMed_21979375_A2Down-0.0478189320
GSE35957Up0.5104287248
GSE36640Up0.6496395713
GSE54402Down-0.2738324821
GSE9593Up0.1812480033
GSE43922Down-0.2480986275
GSE24585Down-0.2031167371
GSE37065Up0.7455998411
GSE28863_A1Down-0.0779405578
GSE28863_A2Up0.0961525261
GSE28863_A3Up0.1802955581
GSE28863_A4Up0.0059180314
GSE48662Up0.0338808679

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040087CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.