HCSGD entry for RNF7
1. General information
| Official gene symbol | RNF7 |
|---|---|
| Entrez ID | 9616 |
| Gene full name | ring finger protein 7 |
| Other gene symbols | CKBBP1 ROC2 SAG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005507 | Copper ion binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA NAS | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008631 | Intrinsic apoptotic signaling pathway in response to oxidative stress | TAS | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0019788 | NEDD8 ligase activity | IDA | molecular_function |
| GO:0031466 | Cul5-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0043066 | Negative regulation of apoptotic process | TAS | biological_process |
| GO:0045116 | Protein neddylation | IDA | biological_process |
| GO:0051775 | Response to redox state | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2883935223 | 0.6314559401 | 0.9868702997 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3602119101 |
| GSE13712_SHEAR | Down | -0.0487594405 |
| GSE13712_STATIC | Up | 0.0996710054 |
| GSE19018 | Up | 0.0268422240 |
| GSE19899_A1 | Up | 0.0687233930 |
| GSE19899_A2 | Up | 0.5343898244 |
| PubMed_21979375_A1 | Up | 0.4005556937 |
| PubMed_21979375_A2 | Up | 0.2299885958 |
| GSE35957 | Down | -0.3299073172 |
| GSE36640 | Up | 0.7463711166 |
| GSE54402 | Up | 0.4671624554 |
| GSE9593 | Up | 0.1413862383 |
| GSE43922 | Down | -0.0145637912 |
| GSE24585 | Down | -0.3159635491 |
| GSE37065 | Down | -0.0014501102 |
| GSE28863_A1 | Down | -0.1399006024 |
| GSE28863_A2 | Down | -0.3358494097 |
| GSE28863_A3 | Down | -0.2317889050 |
| GSE28863_A4 | Down | -0.1542843138 |
| GSE48662 | Down | -0.1185581044 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT019231 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
