HCSGD entry for RNF7


1. General information

Official gene symbolRNF7
Entrez ID9616
Gene full namering finger protein 7
Other gene symbolsCKBBP1 ROC2 SAG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005507Copper ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA NAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDA NAScellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008631Intrinsic apoptotic signaling pathway in response to oxidative stressTASbiological_process
GO:0016567Protein ubiquitinationIEAbiological_process
GO:0019788NEDD8 ligase activityIDAmolecular_function
GO:0031466Cul5-RING ubiquitin ligase complexIDAcellular_component
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0045116Protein neddylationIDAbiological_process
GO:0051775Response to redox stateTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28839352230.63145594010.98687029971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3602119101
GSE13712_SHEARDown-0.0487594405
GSE13712_STATICUp0.0996710054
GSE19018Up0.0268422240
GSE19899_A1Up0.0687233930
GSE19899_A2Up0.5343898244
PubMed_21979375_A1Up0.4005556937
PubMed_21979375_A2Up0.2299885958
GSE35957Down-0.3299073172
GSE36640Up0.7463711166
GSE54402Up0.4671624554
GSE9593Up0.1413862383
GSE43922Down-0.0145637912
GSE24585Down-0.3159635491
GSE37065Down-0.0014501102
GSE28863_A1Down-0.1399006024
GSE28863_A2Down-0.3358494097
GSE28863_A3Down-0.2317889050
GSE28863_A4Down-0.1542843138
GSE48662Down-0.1185581044

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-331-3pMIMAT0000760MIRT019231SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.