HCSGD entry for VPS4B

1. General information

Official gene symbolVPS4B
Entrez ID9525
Gene full namevacuolar protein sorting 4 homolog B (S. cerevisiae)
Other gene symbolsSKD1 SKD1B VPS4-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIMPmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeIDAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0005769Early endosomeIDAcellular_component
GO:0005770Late endosomeIDAcellular_component
GO:0005774Vacuolar membraneIDAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0006200ATP catabolic processIMPbiological_process
GO:0006813Potassium ion transportIEAbiological_process
GO:0007032Endosome organizationIEAbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0010008Endosome membraneIDAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0016032Viral processTASbiological_process
GO:0016197Endosomal transportIDA IMP TASbiological_process
GO:0016887ATPase activityIDA IMPmolecular_function
GO:0031902Late endosome membraneIEAcellular_component
GO:0032367Intracellular cholesterol transportIMPbiological_process
GO:0032510Endosome to lysosome transport via multivesicular body sorting pathwayIMPbiological_process
GO:0033993Response to lipidIDAbiological_process
GO:0042623ATPase activity, coupledNASmolecular_function
GO:0051301Cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07648433950.97249148210.58504629471.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0387775948
GSE13712_SHEARUp0.1489106466
GSE13712_STATICUp0.1999185356
GSE19018Up0.0135065523
GSE19899_A1Up0.3299512634
GSE19899_A2Up0.4409349524
PubMed_21979375_A1Up0.4270558496
PubMed_21979375_A2Up0.4717568823
GSE35957Up0.1589316183
GSE36640Up0.1616887163
GSE54402Up0.0055508155
GSE9593Up0.0560151178
GSE43922Up0.2597943726
GSE24585Down-0.1379510978
GSE37065Up0.1708833185
GSE28863_A1Up0.2920668117
GSE28863_A2Up0.4144893707
GSE28863_A3Down-0.2335495090
GSE28863_A4Up0.1612041955
GSE48662Down-0.1486467001

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020843ProteomicsFunctional MTI (Weak)18668040
hsa-miR-128-3pMIMAT0000424MIRT022010SequencingFunctional MTI (Weak)20371350
hsa-miR-124-3pMIMAT0000422MIRT022778MicroarrayFunctional MTI (Weak)18668037
hsa-miR-32-5pMIMAT0000090MIRT028319SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031206SequencingFunctional MTI (Weak)20371350
hsa-miR-19a-3pMIMAT0000073MIRT031307Reporter assayFunctional MTI14697198
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.