HCSGD entry for VPS4B
1. General information
| Official gene symbol | VPS4B |
|---|---|
| Entrez ID | 9525 |
| Gene full name | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
| Other gene symbols | SKD1 SKD1B VPS4-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IMP | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0005770 | Late endosome | IDA | cellular_component |
| GO:0005774 | Vacuolar membrane | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IMP | biological_process |
| GO:0006813 | Potassium ion transport | IEA | biological_process |
| GO:0007032 | Endosome organization | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IPI | molecular_function |
| GO:0010008 | Endosome membrane | IDA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016197 | Endosomal transport | IDA IMP TAS | biological_process |
| GO:0016887 | ATPase activity | IDA IMP | molecular_function |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
| GO:0032367 | Intracellular cholesterol transport | IMP | biological_process |
| GO:0032510 | Endosome to lysosome transport via multivesicular body sorting pathway | IMP | biological_process |
| GO:0033993 | Response to lipid | IDA | biological_process |
| GO:0042623 | ATPase activity, coupled | NAS | molecular_function |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0764843395 | 0.9724914821 | 0.5850462947 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0387775948 |
| GSE13712_SHEAR | Up | 0.1489106466 |
| GSE13712_STATIC | Up | 0.1999185356 |
| GSE19018 | Up | 0.0135065523 |
| GSE19899_A1 | Up | 0.3299512634 |
| GSE19899_A2 | Up | 0.4409349524 |
| PubMed_21979375_A1 | Up | 0.4270558496 |
| PubMed_21979375_A2 | Up | 0.4717568823 |
| GSE35957 | Up | 0.1589316183 |
| GSE36640 | Up | 0.1616887163 |
| GSE54402 | Up | 0.0055508155 |
| GSE9593 | Up | 0.0560151178 |
| GSE43922 | Up | 0.2597943726 |
| GSE24585 | Down | -0.1379510978 |
| GSE37065 | Up | 0.1708833185 |
| GSE28863_A1 | Up | 0.2920668117 |
| GSE28863_A2 | Up | 0.4144893707 |
| GSE28863_A3 | Down | -0.2335495090 |
| GSE28863_A4 | Up | 0.1612041955 |
| GSE48662 | Down | -0.1486467001 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020843 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022010 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022778 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028319 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031206 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19a-3p | MIMAT0000073 | MIRT031307 | Reporter assay | Functional MTI | 14697198 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
