HCSGD entry for ADAMTS3
1. General information
| Official gene symbol | ADAMTS3 |
|---|---|
| Entrez ID | 9508 |
| Gene full name | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| Other gene symbols | ADAMTS-4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | NAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | NAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | NAS | molecular_function |
| GO:0016485 | Protein processing | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030199 | Collagen fibril organization | NAS | biological_process |
| GO:0030574 | Collagen catabolic process | NAS | biological_process |
| GO:0031012 | Extracellular matrix | TAS | cellular_component |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0481549523 | 0.0650982220 | 0.4854410188 | 0.4817122013 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1328280835 |
| GSE13712_SHEAR | Down | -0.6039528966 |
| GSE13712_STATIC | Down | -0.3981580798 |
| GSE19018 | Down | -1.5275109711 |
| GSE19899_A1 | Up | 0.3971748157 |
| GSE19899_A2 | Up | 0.0449030564 |
| PubMed_21979375_A1 | Up | 0.0837142777 |
| PubMed_21979375_A2 | Up | 0.7051926855 |
| GSE35957 | Down | -0.2365245744 |
| GSE36640 | Down | -0.7078785100 |
| GSE54402 | Up | 0.4322189001 |
| GSE9593 | Down | -0.5900059992 |
| GSE43922 | Up | 1.0218721915 |
| GSE24585 | Up | 0.6267444920 |
| GSE37065 | Down | -0.2018295095 |
| GSE28863_A1 | Down | -0.1673205933 |
| GSE28863_A2 | Up | 0.3961628216 |
| GSE28863_A3 | Up | 0.1193235854 |
| GSE28863_A4 | Up | 0.1454133143 |
| GSE48662 | Down | -0.1757791919 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
