HCSGD entry for ADAMTS3


1. General information

Official gene symbolADAMTS3
Entrez ID9508
Gene full nameADAM metallopeptidase with thrombospondin type 1 motif, 3
Other gene symbolsADAMTS-4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityNASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixNAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008201Heparin bindingIEAmolecular_function
GO:0008270Zinc ion bindingNASmolecular_function
GO:0016485Protein processingIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030199Collagen fibril organizationNASbiological_process
GO:0030574Collagen catabolic processNASbiological_process
GO:0031012Extracellular matrixTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04815495230.06509822200.48544101880.4817122013

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1328280835
GSE13712_SHEARDown-0.6039528966
GSE13712_STATICDown-0.3981580798
GSE19018Down-1.5275109711
GSE19899_A1Up0.3971748157
GSE19899_A2Up0.0449030564
PubMed_21979375_A1Up0.0837142777
PubMed_21979375_A2Up0.7051926855
GSE35957Down-0.2365245744
GSE36640Down-0.7078785100
GSE54402Up0.4322189001
GSE9593Down-0.5900059992
GSE43922Up1.0218721915
GSE24585Up0.6267444920
GSE37065Down-0.2018295095
GSE28863_A1Down-0.1673205933
GSE28863_A2Up0.3961628216
GSE28863_A3Up0.1193235854
GSE28863_A4Up0.1454133143
GSE48662Down-0.1757791919

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.