HCSGD entry for GGPS1

1. General information

Official gene symbolGGPS1
Entrez ID9453
Gene full namegeranylgeranyl diphosphate synthase 1
Other gene symbolsGGPPS GGPPS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004161Dimethylallyltranstransferase activityIEAmolecular_function
GO:0004311Farnesyltranstransferase activityIDAmolecular_function
GO:0004337Geranyltranstransferase activityIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006695Cholesterol biosynthetic processTASbiological_process
GO:0006720Isoprenoid metabolic processIDAbiological_process
GO:0008299Isoprenoid biosynthetic processIEAbiological_process
GO:0033384Geranyl diphosphate biosynthetic processIEAbiological_process
GO:0033386Geranylgeranyl diphosphate biosynthetic processIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045337Farnesyl diphosphate biosynthetic processIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15555907070.80244772990.78363067941.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3001091649
GSE13712_SHEARUp0.0309326271
GSE13712_STATICUp0.0610024094
GSE19018Up0.2945921315
GSE19899_A1Up0.1450794368
GSE19899_A2Up0.5637563114
PubMed_21979375_A1Down-0.7006853350
PubMed_21979375_A2Down-0.0215704573
GSE35957Down-0.1710623902
GSE36640Up0.8730628345
GSE54402Up0.0726532645
GSE9593Up0.2741522072
GSE43922Up0.0384587594
GSE24585Up0.2594663093
GSE37065Up0.0855646513
GSE28863_A1Down-0.0904045068
GSE28863_A2Up0.1003163446
GSE28863_A3Down-0.2336221214
GSE28863_A4Down-0.3010118165
GSE48662Down-0.0871352790

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Zoledronic acidDB00399 APRD01294 | DB06286
Geranyl DiphosphateDB02552 EXPT01640
FARNESYL THIOPYROPHOSPHATEDB04695 -
ISOPENTENYL PYROPHOSPHATEDB04714 -
(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)DB06830 -
(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)DB06931 -
(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUMDB07221 -
[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACIDDB07410 -
FARNESYL DIPHOSPHATEDB07780 -
GERANYLGERANYL DIPHOSPHATEDB07841 -
(1-HYDROXYDODECANE-1,1-DIYL)BIS(PHOSPHONIC ACID)DB07873 -
(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)DB08529 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-5pMIMAT0003886MIRT039170CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045310CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052321CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052559CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.