HCSGD entry for CD33

1. General information

Official gene symbolCD33
Entrez ID945
Gene full nameCD33 molecule
Other gene symbolsSIGLEC-3 SIGLEC3 p67
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48545299950.89704037080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2191469999
GSE13712_SHEARDown-0.0637351782
GSE13712_STATICUp0.0694788446
GSE19018Up0.0199336521
GSE19899_A1Down-0.0595209096
GSE19899_A2Down-0.0826934019
PubMed_21979375_A1Down-0.1674024180
PubMed_21979375_A2Down-0.0791310703
GSE35957Up0.0279360598
GSE36640Up0.0228691288
GSE54402Up0.0128725022
GSE9593Up0.0384101234
GSE43922Up0.2565109224
GSE24585Down-0.0847894708
GSE37065Up0.1340951266
GSE28863_A1Down-0.0269959647
GSE28863_A2Up0.0595588696
GSE28863_A3Up0.3230489653
GSE28863_A4Up0.1533693027
GSE48662Down-0.0742891687

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Gemtuzumab ozogamicinDB00056 BTD00077 | BIOD00077

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019168MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.