HCSGD entry for CD33
1. General information
| Official gene symbol | CD33 |
|---|---|
| Entrez ID | 945 |
| Gene full name | CD33 molecule |
| Other gene symbols | SIGLEC-3 SIGLEC3 p67 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4854529995 | 0.8970403708 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2191469999 |
| GSE13712_SHEAR | Down | -0.0637351782 |
| GSE13712_STATIC | Up | 0.0694788446 |
| GSE19018 | Up | 0.0199336521 |
| GSE19899_A1 | Down | -0.0595209096 |
| GSE19899_A2 | Down | -0.0826934019 |
| PubMed_21979375_A1 | Down | -0.1674024180 |
| PubMed_21979375_A2 | Down | -0.0791310703 |
| GSE35957 | Up | 0.0279360598 |
| GSE36640 | Up | 0.0228691288 |
| GSE54402 | Up | 0.0128725022 |
| GSE9593 | Up | 0.0384101234 |
| GSE43922 | Up | 0.2565109224 |
| GSE24585 | Down | -0.0847894708 |
| GSE37065 | Up | 0.1340951266 |
| GSE28863_A1 | Down | -0.0269959647 |
| GSE28863_A2 | Up | 0.0595588696 |
| GSE28863_A3 | Up | 0.3230489653 |
| GSE28863_A4 | Up | 0.1533693027 |
| GSE48662 | Down | -0.0742891687 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Gemtuzumab ozogamicin | DB00056 | BTD00077 | BIOD00077 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019168 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
