HCSGD entry for TNFSF8
1. General information
| Official gene symbol | TNFSF8 |
|---|---|
| Entrez ID | 944 |
| Gene full name | tumor necrosis factor (ligand) superfamily, member 8 |
| Other gene symbols | CD153 CD30L CD30LG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0043374 | CD8-positive, alpha-beta T cell differentiation | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0050830 | Defense response to Gram-positive bacterium | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2508520991 | 0.9259599407 | 0.9408595954 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0708795237 |
| GSE13712_SHEAR | Up | 0.0889492540 |
| GSE13712_STATIC | Up | 0.0724027205 |
| GSE19018 | Up | 0.1195242218 |
| GSE19899_A1 | Up | 0.0474856493 |
| GSE19899_A2 | Up | 0.1073545016 |
| PubMed_21979375_A1 | Up | 0.9187003994 |
| PubMed_21979375_A2 | Down | -0.0317196782 |
| GSE35957 | Down | -0.0055824170 |
| GSE36640 | Up | 0.0625821020 |
| GSE54402 | Up | 0.3527188202 |
| GSE9593 | Down | -0.0374775123 |
| GSE43922 | Up | 0.1091631915 |
| GSE24585 | Up | 0.0984030482 |
| GSE37065 | Up | 0.1019010415 |
| GSE28863_A1 | Up | 0.2734419067 |
| GSE28863_A2 | Down | -0.3090248083 |
| GSE28863_A3 | Up | 0.0694889369 |
| GSE28863_A4 | Down | -0.0600730057 |
| GSE48662 | Down | -0.0175993586 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
