HCSGD entry for TNFSF8

1. General information

Official gene symbolTNFSF8
Entrez ID944
Gene full nametumor necrosis factor (ligand) superfamily, member 8
Other gene symbolsCD153 CD30L CD30LG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingTASmolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005164Tumor necrosis factor receptor bindingIEAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0043374CD8-positive, alpha-beta T cell differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0050830Defense response to Gram-positive bacteriumIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25085209910.92595994070.94085959541.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0708795237
GSE13712_SHEARUp0.0889492540
GSE13712_STATICUp0.0724027205
GSE19018Up0.1195242218
GSE19899_A1Up0.0474856493
GSE19899_A2Up0.1073545016
PubMed_21979375_A1Up0.9187003994
PubMed_21979375_A2Down-0.0317196782
GSE35957Down-0.0055824170
GSE36640Up0.0625821020
GSE54402Up0.3527188202
GSE9593Down-0.0374775123
GSE43922Up0.1091631915
GSE24585Up0.0984030482
GSE37065Up0.1019010415
GSE28863_A1Up0.2734419067
GSE28863_A2Down-0.3090248083
GSE28863_A3Up0.0694889369
GSE28863_A4Down-0.0600730057
GSE48662Down-0.0175993586

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.