HCSGD entry for KCNB2


1. General information

Official gene symbolKCNB2
Entrez ID9312
Gene full namepotassium voltage-gated channel, Shab-related subfamily, member 2
Other gene symbolsKV2.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005251Delayed rectifier potassium channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0006940Regulation of smooth muscle contractionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77507220850.62555891110.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1389465471
GSE13712_SHEARDown-0.0687638891
GSE13712_STATICDown-0.0569360696
GSE19018Down-0.0080817089
GSE19899_A1Up0.0094008507
GSE19899_A2Down-0.0569219006
PubMed_21979375_A1Up0.0775084875
PubMed_21979375_A2Down-0.0326366459
GSE35957Up0.2586298430
GSE36640Down-0.0317095304
GSE54402Down-0.0150984069
GSE9593Down-0.0195282523
GSE43922Up0.1023887580
GSE24585Down-0.4815436942
GSE37065Up0.0005808149
GSE28863_A1Down-0.1020588428
GSE28863_A2Up0.2264266748
GSE28863_A3Up0.1053685376
GSE28863_A4Up0.0391729474
GSE48662Down-0.0291048349

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.