HCSGD entry for KCNB2


1. General information

Official gene symbolKCNB2
Entrez ID9312
Gene full namepotassium voltage-gated channel, Shab-related subfamily, member 2
Other gene symbolsKV2.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005251Delayed rectifier potassium channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0006940Regulation of smooth muscle contractionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77507220850.62555891110.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1389465471
GSE13712_SHEARDown-0.0687638891
GSE13712_STATICDown-0.0569360696
GSE19018Down-0.0080817089
GSE19899_A1Up0.0094008507
GSE19899_A2Down-0.0569219006
PubMed_21979375_A1Up0.0775084875
PubMed_21979375_A2Down-0.0326366459
GSE35957Up0.2586298430
GSE36640Down-0.0317095304
GSE54402Down-0.0150984069
GSE9593Down-0.0195282523
GSE43922Up0.1023887580
GSE24585Down-0.4815436942
GSE37065Up0.0005808149
GSE28863_A1Down-0.1020588428
GSE28863_A2Up0.2264266748
GSE28863_A3Up0.1053685376
GSE28863_A4Up0.0391729474
GSE48662Down-0.0291048349

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.