HCSGD entry for CACNA2D2

1. General information

Official gene symbolCACNA2D2
Entrez ID9254
Gene full namecalcium channel, voltage-dependent, alpha 2/delta subunit 2
Other gene symbolsCACNA2D LUAC11.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005245Voltage-gated calcium channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0040014Regulation of multicellular organism growthIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046622Positive regulation of organ growthIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048747Muscle fiber developmentIEAbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0060024Rhythmic synaptic transmissionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56073420840.88089958210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1739611239
GSE13712_SHEARDown-0.1353823435
GSE13712_STATICDown-0.1503578174
GSE19018Up0.1215564094
GSE19899_A1Up0.0134423434
GSE19899_A2Up0.1930948369
PubMed_21979375_A1Up0.1349505396
PubMed_21979375_A2Down-0.0009620740
GSE35957Down-0.0783860254
GSE36640Down-0.0537852983
GSE54402Up0.1276241918
GSE9593Down-0.0469313185
GSE43922Up0.0784677029
GSE24585Up0.0922483968
GSE37065Down-0.0700897462
GSE28863_A1Down-0.0316065475
GSE28863_A2Up0.0910734116
GSE28863_A3Up0.1892054548
GSE28863_A4Up0.1026377067
GSE48662Up0.0237038608

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IsradipineDB00270 APRD00298
GabapentinDB00996 APRD00015
NitrendipineDB01054 APRD00421
AmiodaroneDB01118 APRD00288
BepridilDB01244 APRD00727
XP13512DB04922 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.