HCSGD entry for CACNA2D2

1. General information

Official gene symbolCACNA2D2
Entrez ID9254
Gene full namecalcium channel, voltage-dependent, alpha 2/delta subunit 2
Other gene symbolsCACNA2D LUAC11.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005245Voltage-gated calcium channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0040014Regulation of multicellular organism growthIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046622Positive regulation of organ growthIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048747Muscle fiber developmentIEAbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0060024Rhythmic synaptic transmissionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56073420840.88089958210.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1739611239
GSE13712_SHEARDown-0.1353823435
GSE13712_STATICDown-0.1503578174
GSE19018Up0.1215564094
GSE19899_A1Up0.0134423434
GSE19899_A2Up0.1930948369
PubMed_21979375_A1Up0.1349505396
PubMed_21979375_A2Down-0.0009620740
GSE35957Down-0.0783860254
GSE36640Down-0.0537852983
GSE54402Up0.1276241918
GSE9593Down-0.0469313185
GSE43922Up0.0784677029
GSE24585Up0.0922483968
GSE37065Down-0.0700897462
GSE28863_A1Down-0.0316065475
GSE28863_A2Up0.0910734116
GSE28863_A3Up0.1892054548
GSE28863_A4Up0.1026377067
GSE48662Up0.0237038608

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IsradipineDB00270 APRD00298
GabapentinDB00996 APRD00015
NitrendipineDB01054 APRD00421
AmiodaroneDB01118 APRD00288
BepridilDB01244 APRD00727
XP13512DB04922 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.