HCSGD entry for MSC
1. General information
| Official gene symbol | MSC |
|---|---|
| Entrez ID | 9242 |
| Gene full name | musculin |
| Other gene symbols | ABF-1 ABF1 MYOR bHLHa22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0014707 | Branchiomeric skeletal muscle development | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
| GO:0060021 | Palate development | IEA | biological_process |
| GO:0060539 | Diaphragm development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0424674746 | 0.4495546978 | 0.4605119704 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3071050380 |
| GSE13712_SHEAR | Up | 0.0389333011 |
| GSE13712_STATIC | Down | -0.1463280014 |
| GSE19018 | Down | -0.1006318375 |
| GSE19899_A1 | Down | -0.1340392397 |
| GSE19899_A2 | Up | 0.0237781841 |
| PubMed_21979375_A1 | Up | 0.0047601680 |
| PubMed_21979375_A2 | Up | 0.2426694632 |
| GSE35957 | Up | 0.7358362257 |
| GSE36640 | Down | -0.2122937403 |
| GSE54402 | Up | 0.7435376535 |
| GSE9593 | Up | 0.6126006291 |
| GSE43922 | Up | 1.3749240844 |
| GSE24585 | Down | -0.9018464101 |
| GSE37065 | Up | 0.2311217751 |
| GSE28863_A1 | Up | 0.0247026864 |
| GSE28863_A2 | Up | 0.3891959407 |
| GSE28863_A3 | Down | -0.0148341309 |
| GSE28863_A4 | Down | -0.0486250493 |
| GSE48662 | Up | 0.3471523073 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-378a-3p | MIMAT0000732 | MIRT006681 | Luciferase reporter assay | Functional MTI | 21471220 |
| hsa-miR-146a-5p | MIMAT0000449 | MIRT045694 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
