HCSGD entry for MSC


1. General information

Official gene symbolMSC
Entrez ID9242
Gene full namemusculin
Other gene symbolsABF-1 ABF1 MYOR bHLHa22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0014707Branchiomeric skeletal muscle developmentIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0060021Palate developmentIEAbiological_process
GO:0060539Diaphragm developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04246747460.44955469780.46051197041.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3071050380
GSE13712_SHEARUp0.0389333011
GSE13712_STATICDown-0.1463280014
GSE19018Down-0.1006318375
GSE19899_A1Down-0.1340392397
GSE19899_A2Up0.0237781841
PubMed_21979375_A1Up0.0047601680
PubMed_21979375_A2Up0.2426694632
GSE35957Up0.7358362257
GSE36640Down-0.2122937403
GSE54402Up0.7435376535
GSE9593Up0.6126006291
GSE43922Up1.3749240844
GSE24585Down-0.9018464101
GSE37065Up0.2311217751
GSE28863_A1Up0.0247026864
GSE28863_A2Up0.3891959407
GSE28863_A3Down-0.0148341309
GSE28863_A4Down-0.0486250493
GSE48662Up0.3471523073

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-378a-3pMIMAT0000732MIRT006681Luciferase reporter assayFunctional MTI21471220
hsa-miR-146a-5pMIMAT0000449MIRT045694CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.