HCSGD entry for PTPLA
1. General information
| Official gene symbol | PTPLA |
|---|---|
| Entrez ID | 9200 |
| Gene full name | protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A |
| Other gene symbols | CAP HACD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016829 | Lyase activity | IEA | molecular_function |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9536984537 | 0.0007831199 | 0.9999902473 | 0.0524322335 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4104263263 |
| GSE13712_SHEAR | Down | -0.1056035489 |
| GSE13712_STATIC | Up | 0.0250579144 |
| GSE19018 | Down | -0.4966839543 |
| GSE19899_A1 | Down | -1.4421870761 |
| GSE19899_A2 | Down | -0.7318531004 |
| PubMed_21979375_A1 | Down | -1.1954278978 |
| PubMed_21979375_A2 | Down | -0.7581454260 |
| GSE35957 | Up | 0.0253886173 |
| GSE36640 | Up | 0.2126131499 |
| GSE54402 | Down | -0.7090210932 |
| GSE9593 | Down | -0.0618495202 |
| GSE43922 | Down | -0.9640069931 |
| GSE24585 | Up | 0.7898514146 |
| GSE37065 | Down | -0.3752240729 |
| GSE28863_A1 | Down | -1.5373715469 |
| GSE28863_A2 | Down | -0.9718370325 |
| GSE28863_A3 | Down | -0.7374563792 |
| GSE28863_A4 | Up | 0.3045076611 |
| GSE48662 | Down | -0.1668563847 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-652-3p | MIMAT0003322 | MIRT039523 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
