HCSGD entry for PTPLA


1. General information

Official gene symbolPTPLA
Entrez ID9200
Gene full nameprotein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
Other gene symbolsCAP HACD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityTASmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0006633Fatty acid biosynthetic processIEAbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016829Lyase activityIEAmolecular_function
GO:0035335Peptidyl-tyrosine dephosphorylationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95369845370.00078311990.99999024730.0524322335

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4104263263
GSE13712_SHEARDown-0.1056035489
GSE13712_STATICUp0.0250579144
GSE19018Down-0.4966839543
GSE19899_A1Down-1.4421870761
GSE19899_A2Down-0.7318531004
PubMed_21979375_A1Down-1.1954278978
PubMed_21979375_A2Down-0.7581454260
GSE35957Up0.0253886173
GSE36640Up0.2126131499
GSE54402Down-0.7090210932
GSE9593Down-0.0618495202
GSE43922Down-0.9640069931
GSE24585Up0.7898514146
GSE37065Down-0.3752240729
GSE28863_A1Down-1.5373715469
GSE28863_A2Down-0.9718370325
GSE28863_A3Down-0.7374563792
GSE28863_A4Up0.3045076611
GSE48662Down-0.1668563847

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-652-3pMIMAT0003322MIRT039523CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.