HCSGD entry for ZW10
1. General information
| Official gene symbol | ZW10 |
|---|---|
| Entrez ID | 9183 |
| Gene full name | zw10 kinetochore protein |
| Other gene symbols | HZW10 KNTC1AP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000070 | Mitotic sister chromatid segregation | IDA | biological_process |
| GO:0000132 | Establishment of mitotic spindle orientation | IMP | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000775 | Chromosome, centromeric region | IEA | cellular_component |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005828 | Kinetochore microtubule | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006461 | Protein complex assembly | IDA | biological_process |
| GO:0006888 | ER to Golgi vesicle-mediated transport | IMP | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007080 | Mitotic metaphase plate congression | IMP | biological_process |
| GO:0007093 | Mitotic cell cycle checkpoint | IDA | biological_process |
| GO:0007096 | Regulation of exit from mitosis | IDA | biological_process |
| GO:0007126 | Meiosis | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019237 | Centromeric DNA binding | TAS | molecular_function |
| GO:0034501 | Protein localization to kinetochore | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9022984157 | 0.0298951066 | 0.9999902473 | 0.3266372354 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0353220046 |
| GSE13712_SHEAR | Down | -0.3825476302 |
| GSE13712_STATIC | Down | -0.1432011928 |
| GSE19018 | Down | -0.1990049805 |
| GSE19899_A1 | Down | -0.3102384106 |
| GSE19899_A2 | Down | -0.8221111424 |
| PubMed_21979375_A1 | Up | 0.8236555270 |
| PubMed_21979375_A2 | Down | -0.3864081862 |
| GSE35957 | Down | -0.5364277778 |
| GSE36640 | Down | -1.1023735547 |
| GSE54402 | Up | 0.2095989287 |
| GSE9593 | Down | -0.3077199338 |
| GSE43922 | Up | 0.0333701320 |
| GSE24585 | Down | -0.0996881275 |
| GSE37065 | Up | 0.0176694780 |
| GSE28863_A1 | Down | -0.0420804919 |
| GSE28863_A2 | Up | 0.3204980610 |
| GSE28863_A3 | Down | -1.0819497221 |
| GSE28863_A4 | Up | 0.2564842935 |
| GSE48662 | Down | -0.3381586357 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040820 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046629 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
