HCSGD entry for ZW10


1. General information

Official gene symbolZW10
Entrez ID9183
Gene full namezw10 kinetochore protein
Other gene symbolsHZW10 KNTC1AP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000070Mitotic sister chromatid segregationIDAbiological_process
GO:0000132Establishment of mitotic spindle orientationIMPbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000775Chromosome, centromeric regionIEAcellular_component
GO:0000776KinetochoreIDAcellular_component
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0000922Spindle poleIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005828Kinetochore microtubuleIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006461Protein complex assemblyIDAbiological_process
GO:0006888ER to Golgi vesicle-mediated transportIMPbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007080Mitotic metaphase plate congressionIMPbiological_process
GO:0007093Mitotic cell cycle checkpointIDAbiological_process
GO:0007096Regulation of exit from mitosisIDAbiological_process
GO:0007126MeiosisTASbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0019237Centromeric DNA bindingTASmolecular_function
GO:0034501Protein localization to kinetochoreIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90229841570.02989510660.99999024730.3266372354

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0353220046
GSE13712_SHEARDown-0.3825476302
GSE13712_STATICDown-0.1432011928
GSE19018Down-0.1990049805
GSE19899_A1Down-0.3102384106
GSE19899_A2Down-0.8221111424
PubMed_21979375_A1Up0.8236555270
PubMed_21979375_A2Down-0.3864081862
GSE35957Down-0.5364277778
GSE36640Down-1.1023735547
GSE54402Up0.2095989287
GSE9593Down-0.3077199338
GSE43922Up0.0333701320
GSE24585Down-0.0996881275
GSE37065Up0.0176694780
GSE28863_A1Down-0.0420804919
GSE28863_A2Up0.3204980610
GSE28863_A3Down-1.0819497221
GSE28863_A4Up0.2564842935
GSE48662Down-0.3381586357

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-18a-3pMIMAT0002891MIRT040820CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046629CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.