HCSGD entry for SLC6A5

1. General information

Official gene symbolSLC6A5
Entrez ID9152
Gene full namesolute carrier family 6 (neurotransmitter transporter, glycine), member 5
Other gene symbolsGLYT-2 GLYT2 HKPX3 NET1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportTASbiological_process
GO:0005328Neurotransmitter:sodium symporter activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0006820Anion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0015375Glycine:sodium symporter activityTASmolecular_function
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0015711Organic anion transportTASbiological_process
GO:0015804Neutral amino acid transportTASbiological_process
GO:0015807L-amino acid transportTASbiological_process
GO:0015816Glycine transportTASbiological_process
GO:0015849Organic acid transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030001Metal ion transportTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0046942Carboxylic acid transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902475L-alpha-amino acid transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72796010030.89455684050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1300115473
GSE13712_SHEARDown-0.0148474210
GSE13712_STATICDown-0.0279284515
GSE19018Up0.1645995229
GSE19899_A1Up0.1300875157
GSE19899_A2Up0.1043037658
PubMed_21979375_A1Down-0.0142005959
PubMed_21979375_A2Down-0.1035250135
GSE35957Up0.1402655230
GSE36640Up0.1436646149
GSE54402Up0.0043398966
GSE9593Up0.0398788491
GSE43922Up0.0113561598
GSE24585Up0.1295078035
GSE37065Down-0.0176765830
GSE28863_A1Up0.0020388330
GSE28863_A2Down-0.0208354139
GSE28863_A3Up0.2030591651
GSE28863_A4Up0.0449403102
GSE48662Down-0.0593531892

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.