HCSGD entry for SLC6A5


1. General information

Official gene symbolSLC6A5
Entrez ID9152
Gene full namesolute carrier family 6 (neurotransmitter transporter, glycine), member 5
Other gene symbolsGLYT-2 GLYT2 HKPX3 NET1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportTASbiological_process
GO:0005328Neurotransmitter:sodium symporter activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0006820Anion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0015375Glycine:sodium symporter activityTASmolecular_function
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0015711Organic anion transportTASbiological_process
GO:0015804Neutral amino acid transportTASbiological_process
GO:0015807L-amino acid transportTASbiological_process
GO:0015816Glycine transportTASbiological_process
GO:0015849Organic acid transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030001Metal ion transportTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0046942Carboxylic acid transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902475L-alpha-amino acid transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72796010030.89455684050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1300115473
GSE13712_SHEARDown-0.0148474210
GSE13712_STATICDown-0.0279284515
GSE19018Up0.1645995229
GSE19899_A1Up0.1300875157
GSE19899_A2Up0.1043037658
PubMed_21979375_A1Down-0.0142005959
PubMed_21979375_A2Down-0.1035250135
GSE35957Up0.1402655230
GSE36640Up0.1436646149
GSE54402Up0.0043398966
GSE9593Up0.0398788491
GSE43922Up0.0113561598
GSE24585Up0.1295078035
GSE37065Down-0.0176765830
GSE28863_A1Up0.0020388330
GSE28863_A2Down-0.0208354139
GSE28863_A3Up0.2030591651
GSE28863_A4Up0.0449403102
GSE48662Down-0.0593531892

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.