HCSGD entry for SLC6A5
1. General information
| Official gene symbol | SLC6A5 |
|---|---|
| Entrez ID | 9152 |
| Gene full name | solute carrier family 6 (neurotransmitter transporter, glycine), member 5 |
| Other gene symbols | GLYT-2 GLYT2 HKPX3 NET1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003333 | Amino acid transmembrane transport | TAS | biological_process |
| GO:0005328 | Neurotransmitter:sodium symporter activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0015375 | Glycine:sodium symporter activity | TAS | molecular_function |
| GO:0015672 | Monovalent inorganic cation transport | TAS | biological_process |
| GO:0015711 | Organic anion transport | TAS | biological_process |
| GO:0015804 | Neutral amino acid transport | TAS | biological_process |
| GO:0015807 | L-amino acid transport | TAS | biological_process |
| GO:0015816 | Glycine transport | TAS | biological_process |
| GO:0015849 | Organic acid transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030001 | Metal ion transport | TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0046942 | Carboxylic acid transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7279601003 | 0.8945568405 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1300115473 |
| GSE13712_SHEAR | Down | -0.0148474210 |
| GSE13712_STATIC | Down | -0.0279284515 |
| GSE19018 | Up | 0.1645995229 |
| GSE19899_A1 | Up | 0.1300875157 |
| GSE19899_A2 | Up | 0.1043037658 |
| PubMed_21979375_A1 | Down | -0.0142005959 |
| PubMed_21979375_A2 | Down | -0.1035250135 |
| GSE35957 | Up | 0.1402655230 |
| GSE36640 | Up | 0.1436646149 |
| GSE54402 | Up | 0.0043398966 |
| GSE9593 | Up | 0.0398788491 |
| GSE43922 | Up | 0.0113561598 |
| GSE24585 | Up | 0.1295078035 |
| GSE37065 | Down | -0.0176765830 |
| GSE28863_A1 | Up | 0.0020388330 |
| GSE28863_A2 | Down | -0.0208354139 |
| GSE28863_A3 | Up | 0.2030591651 |
| GSE28863_A4 | Up | 0.0449403102 |
| GSE48662 | Down | -0.0593531892 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glycine | DB00145 | NUTR00028 |

