HCSGD entry for RABEP1


1. General information

Official gene symbolRABEP1
Entrez ID9135
Gene full namerabaptin, RAB GTPase binding effector protein 1
Other gene symbolsRAB5EP RABPT5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005768EndosomeIDAcellular_component
GO:0005769Early endosomeIEAcellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0015031Protein transportIEAbiological_process
GO:0030139Endocytic vesicleIDAcellular_component
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0055037Recycling endosomeIEAcellular_component
GO:0061025Membrane fusionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08632853610.93297326850.61668659431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1835081738
GSE13712_SHEARUp0.2666822715
GSE13712_STATICUp0.1730946719
GSE19018Down-0.4242201496
GSE19899_A1Up0.1237655406
GSE19899_A2Down-0.0063917152
PubMed_21979375_A1Up0.3447826261
PubMed_21979375_A2Up0.4561978141
GSE35957Up0.5522433340
GSE36640Down-0.1884381964
GSE54402Up0.2350972517
GSE9593Up0.2437670586
GSE43922Up0.0011475551
GSE24585Up0.0244920744
GSE37065Down-0.0267345752
GSE28863_A1Up0.5158069162
GSE28863_A2Up0.2717345114
GSE28863_A3Down-0.1540277394
GSE28863_A4Up0.1466282072
GSE48662Up0.0139133991

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-373-3pMIMAT0000726MIRT005562Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI21271679
hsa-let-7f-5pMIMAT0000067MIRT051366CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.