HCSGD entry for RABEP1
1. General information
| Official gene symbol | RABEP1 |
|---|---|
| Entrez ID | 9135 |
| Gene full name | rabaptin, RAB GTPase binding effector protein 1 |
| Other gene symbols | RAB5EP RABPT5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030139 | Endocytic vesicle | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0055037 | Recycling endosome | IEA | cellular_component |
| GO:0061025 | Membrane fusion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0863285361 | 0.9329732685 | 0.6166865943 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1835081738 |
| GSE13712_SHEAR | Up | 0.2666822715 |
| GSE13712_STATIC | Up | 0.1730946719 |
| GSE19018 | Down | -0.4242201496 |
| GSE19899_A1 | Up | 0.1237655406 |
| GSE19899_A2 | Down | -0.0063917152 |
| PubMed_21979375_A1 | Up | 0.3447826261 |
| PubMed_21979375_A2 | Up | 0.4561978141 |
| GSE35957 | Up | 0.5522433340 |
| GSE36640 | Down | -0.1884381964 |
| GSE54402 | Up | 0.2350972517 |
| GSE9593 | Up | 0.2437670586 |
| GSE43922 | Up | 0.0011475551 |
| GSE24585 | Up | 0.0244920744 |
| GSE37065 | Down | -0.0267345752 |
| GSE28863_A1 | Up | 0.5158069162 |
| GSE28863_A2 | Up | 0.2717345114 |
| GSE28863_A3 | Down | -0.1540277394 |
| GSE28863_A4 | Up | 0.1466282072 |
| GSE48662 | Up | 0.0139133991 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT005562 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 21271679 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051366 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
