HCSGD entry for CCNB2
1. General information
| Official gene symbol | CCNB2 |
|---|---|
| Entrez ID | 9133 |
| Gene full name | cyclin B2 |
| Other gene symbols | HsT17299 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | IEA | biological_process |
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007077 | Mitotic nuclear envelope disassembly | TAS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0040007 | Growth | IEA | biological_process |
| GO:0043029 | T cell homeostasis | IEA | biological_process |
| GO:0048538 | Thymus development | IEA | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9904566278 | 0.0001123704 | 0.9999902473 | 0.0192058442 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7377628074 |
| GSE13712_SHEAR | Down | -0.2126293432 |
| GSE13712_STATIC | Down | -0.1883330957 |
| GSE19018 | Up | 0.2761241147 |
| GSE19899_A1 | Down | -1.1247727386 |
| GSE19899_A2 | Down | -1.6971191979 |
| PubMed_21979375_A1 | Down | -1.7375963892 |
| PubMed_21979375_A2 | Down | -2.3635907069 |
| GSE35957 | Down | -1.7961880373 |
| GSE36640 | Down | -1.9364530975 |
| GSE54402 | Down | -0.6572927778 |
| GSE9593 | Down | -0.7420546999 |
| GSE43922 | Down | -2.7311829379 |
| GSE24585 | Up | 0.1036229812 |
| GSE37065 | Down | -0.8182528389 |
| GSE28863_A1 | Down | -0.1439486755 |
| GSE28863_A2 | Up | 0.0489873217 |
| GSE28863_A3 | Down | -0.3453112721 |
| GSE28863_A4 | Up | 0.0813228289 |
| GSE48662 | Down | -2.2124439782 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046347 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051400 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051866 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051889 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052637 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
