HCSGD entry for CCNB2


1. General information

Official gene symbolCCNB2
Entrez ID9133
Gene full namecyclin B2
Other gene symbolsHsT17299
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityIEAbiological_process
GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007049Cell cycleIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0040007GrowthIEAbiological_process
GO:0043029T cell homeostasisIEAbiological_process
GO:0048538Thymus developmentIEAbiological_process
GO:0051301Cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99045662780.00011237040.99999024730.0192058442

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.7377628074
GSE13712_SHEARDown-0.2126293432
GSE13712_STATICDown-0.1883330957
GSE19018Up0.2761241147
GSE19899_A1Down-1.1247727386
GSE19899_A2Down-1.6971191979
PubMed_21979375_A1Down-1.7375963892
PubMed_21979375_A2Down-2.3635907069
GSE35957Down-1.7961880373
GSE36640Down-1.9364530975
GSE54402Down-0.6572927778
GSE9593Down-0.7420546999
GSE43922Down-2.7311829379
GSE24585Up0.1036229812
GSE37065Down-0.8182528389
GSE28863_A1Down-0.1439486755
GSE28863_A2Up0.0489873217
GSE28863_A3Down-0.3453112721
GSE28863_A4Up0.0813228289
GSE48662Down-2.2124439782

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-23b-3pMIMAT0000418MIRT046347CLASHFunctional MTI (Weak)23622248
hsa-let-7f-5pMIMAT0000067MIRT051400CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051866CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051889CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052637CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.