HCSGD entry for PRPF3
1. General information
| Official gene symbol | PRPF3 |
|---|---|
| Entrez ID | 9129 |
| Gene full name | PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) |
| Other gene symbols | HPRP3 HPRP3P PRP3 Prp3p RP18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IEA NAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0019013 | Viral nucleocapsid | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0046540 | U4/U6 x U5 tri-snRNP complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0746108924 | 0.5883247635 | 0.5793767257 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1015794536 |
| GSE13712_SHEAR | Up | 0.1008132122 |
| GSE13712_STATIC | Down | -0.0107003901 |
| GSE19018 | Down | -0.7602906461 |
| GSE19899_A1 | Up | 0.2609270061 |
| GSE19899_A2 | Up | 0.7209482415 |
| PubMed_21979375_A1 | Up | 0.9640289408 |
| PubMed_21979375_A2 | Up | 1.1258995042 |
| GSE35957 | Down | -0.9719572506 |
| GSE36640 | Down | -0.4278817939 |
| GSE54402 | Up | 0.4140917843 |
| GSE9593 | Down | -0.2211350446 |
| GSE43922 | Up | 0.6572543459 |
| GSE24585 | Down | -0.1201865073 |
| GSE37065 | Down | -0.0027643360 |
| GSE28863_A1 | Up | 0.1577040709 |
| GSE28863_A2 | Up | 0.2069083173 |
| GSE28863_A3 | Up | 0.0496868339 |
| GSE28863_A4 | Down | -0.0273050087 |
| GSE48662 | Down | -0.0445912786 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
