HCSGD entry for PRPF3


1. General information

Official gene symbolPRPF3
Entrez ID9129
Gene full namePRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)
Other gene symbolsHPRP3 HPRP3P PRP3 Prp3p RP18
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000375RNA splicing, via transesterification reactionsTASbiological_process
GO:0000398MRNA splicing, via spliceosomeIEA NASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005681Spliceosomal complexNAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006397MRNA processingTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0015030Cajal bodyIDAcellular_component
GO:0016607Nuclear speckIEAcellular_component
GO:0019013Viral nucleocapsidIEAcellular_component
GO:0042802Identical protein bindingIPImolecular_function
GO:0046540U4/U6 x U5 tri-snRNP complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07461089240.58832476350.57937672571.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1015794536
GSE13712_SHEARUp0.1008132122
GSE13712_STATICDown-0.0107003901
GSE19018Down-0.7602906461
GSE19899_A1Up0.2609270061
GSE19899_A2Up0.7209482415
PubMed_21979375_A1Up0.9640289408
PubMed_21979375_A2Up1.1258995042
GSE35957Down-0.9719572506
GSE36640Down-0.4278817939
GSE54402Up0.4140917843
GSE9593Down-0.2211350446
GSE43922Up0.6572543459
GSE24585Down-0.1201865073
GSE37065Down-0.0027643360
GSE28863_A1Up0.1577040709
GSE28863_A2Up0.2069083173
GSE28863_A3Up0.0496868339
GSE28863_A4Down-0.0273050087
GSE48662Down-0.0445912786

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.