HCSGD entry for PDLIM1


1. General information

Official gene symbolPDLIM1
Entrez ID9124
Gene full namePDZ and LIM domain 1
Other gene symbolsCLIM1 CLP-36 CLP36 hCLIM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:0003713Transcription coactivator activityIEAmolecular_function
GO:0005667Transcription factor complexIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006979Response to oxidative stressTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12784455380.07548143690.72726817890.5192949426

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6043424254
GSE13712_SHEARUp0.2199517760
GSE13712_STATICUp0.1939679762
GSE19018Up0.1069572566
GSE19899_A1Up0.4270546317
GSE19899_A2Up0.5905747386
PubMed_21979375_A1Up0.5337959376
PubMed_21979375_A2Up0.6679996036
GSE35957Down-0.7651189992
GSE36640Up1.1722062343
GSE54402Down-0.5278575441
GSE9593Down-0.1500126652
GSE43922Up0.4695956629
GSE24585Down-0.5608246257
GSE37065Down-1.3287124515
GSE28863_A1Down-0.2241599410
GSE28863_A2Down-0.1801380486
GSE28863_A3Down-0.2167470527
GSE28863_A4Up0.0133324895
GSE48662Up0.2680116932

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029619MicroarrayFunctional MTI (Weak)19088304
hsa-miR-504-5pMIMAT0002875MIRT041081CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044643CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049434CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.