HCSGD entry for PDLIM1
1. General information
| Official gene symbol | PDLIM1 |
|---|---|
| Entrez ID | 9124 |
| Gene full name | PDZ and LIM domain 1 |
| Other gene symbols | CLIM1 CLP-36 CLP36 hCLIM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0003713 | Transcription coactivator activity | IEA | molecular_function |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006979 | Response to oxidative stress | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1278445538 | 0.0754814369 | 0.7272681789 | 0.5192949426 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6043424254 |
| GSE13712_SHEAR | Up | 0.2199517760 |
| GSE13712_STATIC | Up | 0.1939679762 |
| GSE19018 | Up | 0.1069572566 |
| GSE19899_A1 | Up | 0.4270546317 |
| GSE19899_A2 | Up | 0.5905747386 |
| PubMed_21979375_A1 | Up | 0.5337959376 |
| PubMed_21979375_A2 | Up | 0.6679996036 |
| GSE35957 | Down | -0.7651189992 |
| GSE36640 | Up | 1.1722062343 |
| GSE54402 | Down | -0.5278575441 |
| GSE9593 | Down | -0.1500126652 |
| GSE43922 | Up | 0.4695956629 |
| GSE24585 | Down | -0.5608246257 |
| GSE37065 | Down | -1.3287124515 |
| GSE28863_A1 | Down | -0.2241599410 |
| GSE28863_A2 | Down | -0.1801380486 |
| GSE28863_A3 | Down | -0.2167470527 |
| GSE28863_A4 | Up | 0.0133324895 |
| GSE48662 | Up | 0.2680116932 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029619 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041081 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044643 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049434 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
