HCSGD entry for CCT6A


1. General information

Official gene symbolCCT6A
Entrez ID908
Gene full namechaperonin containing TCP1, subunit 6A (zeta 1)
Other gene symbolsCCT-zeta CCT-zeta-1 CCT6 Cctz HTR3 MoDP-2 TCP-1-zeta TCP20 TCPZ TTCP20
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleIEAcellular_component
GO:0002199Zona pellucida receptor complexIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIEA TAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005832Chaperonin-containing T-complexIEAcellular_component
GO:0005874MicrotubuleIDAcellular_component
GO:0006457Protein foldingIEA TASbiological_process
GO:0007339Binding of sperm to zona pellucidaIEAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044297Cell bodyIEAcellular_component
GO:0051082Unfolded protein bindingIEAmolecular_function
GO:0051084'de novo' posttranslational protein foldingTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45744453100.25225557540.99999024730.9643270113

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4099207127
GSE13712_SHEARUp0.0615872933
GSE13712_STATICUp0.1269652598
GSE19018Down-0.9930826968
GSE19899_A1Up0.3397778541
GSE19899_A2Up0.0530954596
PubMed_21979375_A1Up0.0667267986
PubMed_21979375_A2Up0.0239314803
GSE35957Down-0.0155463888
GSE36640Down-0.2516397098
GSE54402Up0.3106248819
GSE9593Down-0.3168099507
GSE43922Up0.1989424373
GSE24585Down-0.2934207602
GSE37065Down-0.1382395581
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.6880658399

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-32-5pMIMAT0000090MIRT028359SequencingFunctional MTI (Weak)20371350
hsa-miR-324-3pMIMAT0000762MIRT042874CLASHFunctional MTI (Weak)23622248
hsa-miR-30e-5pMIMAT0000692MIRT044158CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045101CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045502CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050689CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050996CLASHFunctional MTI (Weak)23622248
hsa-miR-3663-3pMIMAT0018085MIRT052868CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.