HCSGD entry for CCT6A
1. General information
| Official gene symbol | CCT6A |
|---|---|
| Entrez ID | 908 |
| Gene full name | chaperonin containing TCP1, subunit 6A (zeta 1) |
| Other gene symbols | CCT-zeta CCT-zeta-1 CCT6 Cctz HTR3 MoDP-2 TCP-1-zeta TCP20 TCPZ TTCP20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001669 | Acrosomal vesicle | IEA | cellular_component |
| GO:0002199 | Zona pellucida receptor complex | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005832 | Chaperonin-containing T-complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0006457 | Protein folding | IEA TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | IEA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4574445310 | 0.2522555754 | 0.9999902473 | 0.9643270113 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4099207127 |
| GSE13712_SHEAR | Up | 0.0615872933 |
| GSE13712_STATIC | Up | 0.1269652598 |
| GSE19018 | Down | -0.9930826968 |
| GSE19899_A1 | Up | 0.3397778541 |
| GSE19899_A2 | Up | 0.0530954596 |
| PubMed_21979375_A1 | Up | 0.0667267986 |
| PubMed_21979375_A2 | Up | 0.0239314803 |
| GSE35957 | Down | -0.0155463888 |
| GSE36640 | Down | -0.2516397098 |
| GSE54402 | Up | 0.3106248819 |
| GSE9593 | Down | -0.3168099507 |
| GSE43922 | Up | 0.1989424373 |
| GSE24585 | Down | -0.2934207602 |
| GSE37065 | Down | -0.1382395581 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.6880658399 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-32-5p | MIMAT0000090 | MIRT028359 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042874 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30e-5p | MIMAT0000692 | MIRT044158 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045101 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045502 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050689 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050996 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3663-3p | MIMAT0018085 | MIRT052868 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
