HCSGD entry for SLC7A6


1. General information

Official gene symbolSLC7A6
Entrez ID9057
Gene full namesolute carrier family 7 (amino acid transporter light chain, y+L system), member 6
Other gene symbolsLAT-2 LAT3 y+LAT-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006461Protein complex assemblyTASbiological_process
GO:0006520Cellular amino acid metabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006865Amino acid transportTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0015171Amino acid transmembrane transporter activityIEAmolecular_function
GO:0015297Antiporter activityIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0050900Leukocyte migrationTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14047481100.16354300750.75280630720.7815438998

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2439024083
GSE13712_SHEARUp0.1616181872
GSE13712_STATICUp0.1743692977
GSE19018Down-0.8522862611
GSE19899_A1Up0.0799489920
GSE19899_A2Up0.6839388126
PubMed_21979375_A1Up0.0699993613
PubMed_21979375_A2Up1.3020204567
GSE35957Up0.2866498237
GSE36640Up0.2592558144
GSE54402Up0.3300243512
GSE9593Down-0.2745380177
GSE43922Up0.6338168419
GSE24585Down-0.6092744219
GSE37065Down-0.2178770628
GSE28863_A1Down-0.0233653560
GSE28863_A2Down-0.1857071095
GSE28863_A3Down-0.7355967033
GSE28863_A4Up0.2480626485
GSE48662Down-0.2298248314

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-3pMIMAT0000088MIRT001761Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI16239240
hsa-miR-125b-5pMIMAT0000423MIRT004987MicroarrayFunctional MTI (Weak)17891175
hsa-miR-375MIMAT0000728MIRT020026MicroarrayFunctional MTI (Weak)20215506
hsa-miR-98-5pMIMAT0000096MIRT027832MicroarrayFunctional MTI (Weak)19088304
hsa-miR-193b-3pMIMAT0002819MIRT041607CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.